INVESTIGATION OF COMPLEX COMPOUNDS OF GUANIDINE ACRYLATE WITH MAGNESIUM IONS
Abstract
Metal ions in a composition of the polymer compounds can serve as model objects of biological systems and show a number of important biological functions. Particular practical interest are represent polymeric materials containing stabilized metal ions such as silver; copper; iron; cobalt; nickel and magnesium. It is known that the guanidine-containing polymers have intrinsic antibacterial properties. Therefore; the combination of properties polyguanidines (biological activity; bactericidal and hydrodynamic properties) and metal ions (optical; biological; thermal; electrical properties) causes the forward-received new features based on these polymeric metal complexes. By IR spectroscopy and X-ray diffraction the structure of resulting polymer complex compound was studied. Infrared spectral studies have shown that the addition of magnesium ions to the structure of the polyacrylate guanidine leads to significant changes in their IR spectra. It was found that the Mg2+ ions actively interact with the oxygen atom of a carboxylate ion; and the nitrogen atom of the amino group of guanidine polyacrylate forms a new coordination compound. X-ray data showed that the initial polymer polyacrylate guanidine has diffraction pattern of the crystalline substance. The complex polymer of polyacrylate guanidine/Mg2+ has a more amorphous structure; as indicated by characteristic broad lines (halo) on the X-ray pattern. It was found that the obtained complex compound of polyacrylate guanidine/Mg2+ does not preserve the original features of the polymer. This is possible due to the fact that magnesium ions penetrating into the polymer matrix partially destroy it and form a new complex compound.
Forcitation:
Isupova Z.Yu.; Elcheparova S.A.; Zhansitov A.A.; Khashirova S.Yu.; Ligidov M.Kh.; Pakhomov S.I. Investigation of complex compounds of guanidine acrylate with magnesium ions. Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol. 2017. V. 60. N 5. P. 63-67References
Alesenko A.V., Burlakova E.B., Pantaz E.A. Effect of sphingomyelin on RNA-polymerase activity in the cell nucleus of normal and regenerating rat liver. Biokhimiia. 1984. V. 49. N 4. P. 621-628.
Alessenko A.V., Burlakova E.B. Functional role of phospholipids in the nuclear events. Bioelectrochemistry. 2002. V. 58. N 1. P. 13-21. DOI: 10.1016/S1567-5394(02)00135-4.
Hutten A., Sudfeld D., Ennen I., Reiss G., Hachmann W., Heinzmann U., Wojczykowski K., Jutzi P., Saikaly W., Thomas G. New magnetic nanoparticles for biotechnology. J. Biotechnol.2004. V. 112. N 1-2. P. 47-63. DOI: 10.1016/j.jbiotec.2004.04.019.
Polymers in pharmacy. Ed. by Tentsova A.N.; Alyushina M.T. М.: Meditsina. 1985. 256 p. (in Russian).
Privalova E.G., Nikityuk V.G. On the obtaining technology of high carotenoid rosehip drug. Provizor. 1999. N 11. P. 43-45 (in Russian).
Egorova E.M., Revina A.A., Rostovshchikova T.N., Kiseleva O.I. Bactericidal and catalytic properties of stable metal nanoparticles in reverse micelles. Vestn. MGU. Ser. 2. Khimiya. 2001. V. 42. N 5. P. 332-338 (in Russian).
Baiytukalov T.A., Lobaeva T.A., Glushchenko N.N., Bogoslovskaya O.A., Olkhovskaya I.P., Orekhova O.I. Research of regenerating activity of ultrafine magnesium powder in the composition of dosage forms. Vestn. RUDN. Ser. Meditsina. 2004. V. 1. N 25. P. 20-26 (in Russian).
