АНАЛИТИЧЕСКИЕ МЕТОДЫ ДЛЯ ОЦЕНКИ ФАРМАЦЕВТИЧЕСКОГО ЗАГРЯЗНЕНИЯ РЕК МИРА; ОБЗОР
Аннотация
Недавние сообщения о новых проблемах загрязнения, вызванных присутствием лекарств в водной среде, вызвали большой интерес к исследованиям, направленным на анализ и смягчение связанных с этим экологических рисков, а также степени этого загрязнения. Основными источниками фармацевтических загрязнителей в природных озерах и реках являются сточные воды клиник, сточные воды фармацевтического производства и сточные воды жилых домов, загрязненные экскрементами потребителей лекарств. При оценке состояния рек фармацевтические загрязнители были определены как одни из новых загрязнителей. Предыдущие исследования показали, что примесями в широко используемых фармацевтических препаратах являются нестероидные противовоспалительные препараты, антибиотики, антиретровирусные и противораковые препараты. Кроме того, этот обзор демонстрирует использование аналитических методов для изучения этих загрязнителей в различных видах речной воды. Из-за их чрезвычайно низких концентраций в водной среде (примерно в диапазоне от нг/л до г/л) для идентификации и количественного определения этих продуктов необходимо применять методику высокочувствительного и селективного многокомпонентного одновременного анализа. Этот аналитический метод обеспечивает гибкие и надежные средства для выявления и оценки фармацевтических загрязнителей в пробах речной воды путем сочетания твердофазной экстракции и масс-спектрометрических методов. SPE-LC/MS/MS – основной метод оценки уровня загрязнения.
Для цитирования:
Джамур Джасим. M.С. Аналитические методы для оценки фармацевтического загрязнения рек мира; обзор. Изв. вузов. Химия и хим. технология. 2024. Т. 67. Вып. 5. С. 6-16. DOI: 10.6060/ivkkt.20246705.7017.
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